Uso de las proteínas derivadas de la matriz del esmalte en la Odontología.

Abstract

Periodontitis is a serious public health problem, ranked as the second most common cause of tooth loss, with consequences such as gingival recession, the creation of periodontal pockets and loss of periodontal attachment in general. For this systematic review, 130 articles focused on the main topic and annexes to it were taken into account, of which 20 articles were chosen, the selected articles were published between the years 2000-2023 and were searched in different platforms such as SciELO, PubMed and LILACS; and in different languages such as Spanish, English and Portuguese. In order to reverse the progression of Periodontal Disease, a compound of proteins derived from the enamel matrix (PDME) that promotes tissue regeneration was introduced to the dental market. In humans, PDME are present in the embryonic period during the cementogenesis process and disappear when the dental enamel begins to form; they are composed of 90% amelogenin and other materials that are part of its intracellular and extracellular material and all of them are an important part of the modulation and remodeling of tissues such as alveolar bone, acellular cementum and periodontal ligament. It is used as a complement in the therapy of reimplanted teeth, gingival recession, it is part of the antimicrobial treatment and pulp therapy thanks to its ability to regenerate dentin.