Hemofilia en paciente pediátrico.

Abstract

Hemophilia is defined as a coagulation disorder, to which a genetic origin, with a recessive inheritance pattern linked to the X chromosome, where coagulation factors VIII and IX are altered, causing a functional deficit and quantitative which is called, respectively, hemophilia A and B (Martínez Sánchez, Álvarez Hernández, Ruiz Mejía, Jaramillo Jaramillo, Builes Restrepo, & Villegas Álzate, 2018). Its incidence is 1.5 cases per million inhabitants/year, increasing to 15 cases per million inhabitants/year in people over 85 years of age. Mortality is 30%. (Milanesio, Olmedo, Caeiro, Tabares, & Montivero, 2022) The most associated diseases include: neoplasms, autoimmune, drugs and period postpartum. In 50% it is idiopathic. Its symptoms are variable, from mild to life-threatening. Within your main manifestations include ecchymosis, bleeding and hemarthrosis; all this data generate suspicion for the diagnosis. (Gallo, Castillo, Villalobos, Caro, & Arroyo, 2022).