Evaluación del riesgo ambiental del contaminante emergente cefalexina, utilizando la especie Danio rerio como bioindicador.

Abstract

The objective of this study was to assess the environmental risk of the drug cephalexin using the Danio rerio species as a bioindicator. Juvenile zebrafish were used in an unforced exposure assay. The assay was conducted in a multi-compartment system with seven compartments. A linear contamination gradient was created with six concentrations (50, 100, 200, 400, 600, and 800 mg/L of cephalexin) plus a control. The treatments and the control were tested in triplicate. These treatments were placed individually in a compartment of the system. Once the linear contamination gradient was prepared, three organisms were introduced into each compartment, for a total of 21 organisms per system and 63 organisms per test. The experiments were conducted in complete darkness.